The 4MP camera sensor is based on 6.5um pixel with full well of 30,000e. The ORCA-Flash4.0 has QE of over 70% at 600 nm and 50% at 750 nm, and has only 1.3e of read noise at 100fps at full-resolution. This unique combination of high QE and low noise, in the absence of EM-CCD multiplicative noise, means that images are no longer limited by the camera.
The new camera datasheet has comparison with competitors:
The uniformity comparison:
A very nice whitepaper explains the comparisons and the new sensor features.